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Laboratory methods in antimicrobial chemotherapy

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Published by Churchill Livingstone, distributed by Longman in Edinburgh, New York, New York .
Written in English

Subjects:

  • Microbial sensitivity tests.,
  • Antibiotics -- Analysis.,
  • Antibiotics -- Laboratory manuals.,
  • Anti-infective agents -- Laboratory manuals.,
  • Microbial sensitivity tests.

Book details:

Edition Notes

Statementedited by David S. Reeves ... [et al.] ; foreword by Lawrence P. Garrod.
ContributionsReeves, David S.
Classifications
LC ClassificationsQR69.A57 L3
The Physical Object
Pagination272 p. :
Number of Pages272
ID Numbers
Open LibraryOL4739499M
ISBN 10044301664X
LC Control Number78040409

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In the forerunner of this book appeared as Laboratory Methods in Antimicrobial Therapy (Editors Reeves, Philips, Williams and Wise). In its Foreword Professor L.P. Garrod likened an antimicrobial prescriber who lacked laboratory assistance to a mariner without a chart of compass. It is. A variety of laboratory methods can be used to measure the in vitro susceptibility of bacteria to antimicrobial agents. This document describes standard broth dilution (macrodilution and microdilution) and agar dilution techniques, and it includes a series of . Antimicrobial Chemotherapy. Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy. Well-respected and widely regarded as the most comprehensive text in the field, Antibiotic and Chemotherapy, 9th Edition by Drs. Finch, Greenwood, Whitley, and Norrby, provides globally relevant coverage of all types of antimicrobial agents used in human medicine, including all antiviral, antiprotozoan and anthelminthic agents.

Modern chemotherapy has been dated to the work of Paul Ehrlich in Germany, who sought systematically to discover effective agents to treat trypanosomiasis and syphilis. He discovered p -rosaniline, which has antitrypanosomal effects, and arsphenamine, which is effective against syphilis. Guideline — Laboratory methodologies for bacterial antimicrobial susceptibility testing 4 OIE Terrestrial Manual i) disk diffusion, ii) broth dilution, iii) agar dilution. a) Disk diffusion method Disk diffusion refers to the diffusion of an antimicrobial agent of a specified concentration from disks, tablets. Antibiotics: substances produced as metabolic products of one microorganism, which inhibit or kill other microorganisms. Antimicrobial chemotherapeutic chemicals: chemicals synthesized in the laboratory, which can be used therapeutically on microorganisms. Chemotherapy may involve drugs that target cancerous cells or tissues, or it may involve antimicrobial drugs that target infectious microorganisms. Antimicrobial drugs typically work by destroying or interfering with microbial structures and enzymes, either killing microbial cells or inhibiting of their growth.

These methods significantly reduce the time for pathogen identification and antimicrobial susceptibility from days to hours compared with conventional techniques. In most hospital microbiology laboratories, the average time for identification and antimicrobial susceptibility test results is approximately 40 h by traditional microbiological : Füsun Can, Onur Karatuna. Antimicrobial Chemotherapy (7th edition) Download the book – PDF File – MB Download Join am-medicine Group Content Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial. Medical Microbiology: A Guide to Microbial Infections: Pathogenesis, Immunity, Laboratory Investigation and Control. 19th edition, by Michael R. Barer, Will Irving, Andrew Swann, and Nelun Perera "Medical microbiology concerns the nature, distribution and activities of microbes and their impact on health and wellbeing. Most antimicrobial susceptibility testing methods that are used in the clinical laboratory are well characterized and have been standardized by the Clinical and Laboratory Standards Institute (CLSI). However, controversies exist about which test methods provide the most useful information, how to best report these results to clinicians, and how.